Online consultation on experts’ views on digital competence

The objective of this investigation was to provide another perspective on what it means to be digitally competent today, in addition to reviews of literature and current frameworks for the development of digital competence, 5 all of which constitute part of the wider IPTS Digital Competence Project (DIGCOMP). Some common ground exists at a general level in defining digital competence in terms of knowledge, skills, and attitudes, which may be hierarchically organised. However, this does not provide the clarity needed by teachers, employers, citizens – all those who are responsible for digital competence development, be it their own or other people’s ‐ to make informed decisions. Further work is needed to create a common language that helps to enhance understanding across the worlds of research, education, training, and work. This will make it easier for citizens and employers to see what digital competence entails and how it is relevant to their jobs and more generally, their lives

Extended Benefit-Cost Analysis of Management Alternatives: Pagbilao Mangrove Forest

Mangroves are important fish hatcheries. It prevents coastal erosion and provides timber resources. However, it limits land access to coastal and fishpond areas. This article presents a cost-benefit analysis on mangrove preservation.natural resources and environment, environmental issues

Simultaneous amplicon sequencing to explore co- occurrence patterns of bacterial, archaeal and eukaryotic microorganisms in rumen microbial communities

Ruminants rely on a complex rumen microbial community to convert dietary plant material to energy-yielding products. Here we developed a method to simultaneously analyze the community's bacterial and archaeal 16S rRNA genes, ciliate 18S rRNA genes and anaerobic fungal internal transcribed spacer 1 genes using 12 DNA samples derived from 11 different rumen samples from three host species (Ovis aries, Bos taurus, Cervus elephas) and multiplex 454 Titanium pyrosequencing. We show that the mixing ratio of the group-specific DNA templates before emulsion PCR is crucial to compensate for differences in amplicon length. This method, in contrast to using a non-specific universal primer pair, avoids sequencing non-targeted DNA, such as plant- or endophyte-derived rRNA genes, and allows increased or decreased levels of community structure resolution for each microbial group as needed. Communities analyzed with different primers always grouped by sample origin rather than by the primers used. However, primer choice had a greater impact on apparent archaeal community structure than on bacterial community structure, and biases for certain methanogen groups were detected. Co-occurrence analysis of microbial taxa from all three domains of life suggested strong within- and between-domain correlations between different groups of microorganisms within the rumen. The approach used to simultaneously characterize bacterial, archaeal and eukaryotic components of a microbiota should be applicable to other communities occupying diverse habitats

Reversals in past long-term trends in educational inequalities in life expectancy for selected European countries

BACKGROUND: Across Europe, socioeconomic inequalities in mortality are large and persistent. To better understand the drivers of past trends in socioeconomic mortality inequalities, we identified phases and potential reversals in long-term trends in educational inequalities in remaining life expectancy at age 30 (e30), and assessed the contributions of mortality changes among the low-educated and the high-educated at different ages. METHODS: We used individually linked annual mortality data by educational level (low, middle and high), sex and single age (30+) from 1971/1972 onwards for England and Wales, Finland and Italy (Turin). We applied segmented regression to trends in educational inequalities in e30 (e30 high-educated minus e30 low-educated) and employed a novel demographic decomposition technique. RESULTS: We identified several phases and breakpoints in the trends in educational inequalities in e30. The long-term increases (Finnish men, 1982–2008; Finnish women, 1985–2017; and Italian men, 1976–1999) were driven by faster mortality declines among the high-educated aged 65–84, and by mortality increases among the low-educated aged 30–59. The long-term decreases (British men, 1976–2008, and Italian women, 1972–2003) were driven by faster mortality improvements among the low-educated than among the high-educated at age 65+. The recent stagnation of increasing inequality (Italian men, 1999) and reversals from increasing to decreasing inequality (Finnish men, 2008) and from decreasing to increasing inequality (British men, 2008) were driven by mortality trend changes among the low-educated aged 30–54. CONCLUSION: Educational inequalities are plastic. Mortality improvements among the low-educated at young ages are imperative for achieving long-term decreases in educational inequalities in e30

Phylogenetic Placement of Exact Amplicon Sequences Improves Associations with Clinical Information

Janssen S, McDonald D, Gonzalez A, et al. Phylogenetic Placement of Exact Amplicon Sequences Improves Associations with Clinical Information. mSystems. 2018;3(3):e00021-18

Genome-wide analysis of single nucleotide polymorphisms and copy number variants in fibromyalgia suggest a role for the central nervous system

Fibromyalgia (FM) is a highly disabling syndrome defined by a low pain threshold and a permanent state of pain. The mechanisms explaining this complex disorder remain unclear, and its genetic factors have not yet been identified. With the aim of elucidating FM genetic susceptibility factors, we selected 313 FM cases having low comorbidities, and we genotyped them on the Illumina 1 million duo array. Genotypic data from 220 control women (Illumina 610k array) was obtained for genome-wide association scan (GWAS) analysis. Copy number variants in FM susceptibility were analyzed by array comparative genomic hybridization (aCGH) experiments on pooled samples using the Agilent 2 × 400K platform. No single nucleotide polymorphism (SNP) reached GWAS association threshold, but 21 of the most associated SNPs were chosen for replication in 952 cases and 644 controls. Four of the SNPs selected for replication showed a nominal association in the joint analysis, and rs11127292 (MYT1L) was found to be associated to FM with low comorbidities (P = 4.28 × 10−5, odds ratio [95% confidence interval] = 0.58 [0.44-0.75]). aCGH detected 5 differentially hybridized regions. They were followed up, and an intronic deletion in NRXN3 was demonstrated to be associated to female cases of FM with low levels of comorbidities (P = .021, odds ratio [95% confidence interval] = 1.46 [1.05-2.04]). Both GWAS and aCGH results point to a role for the central nervous system in FM genetic susceptibility. If the proposed FM candidate genes were further validated in replication studies, this would highlight a neurocognitive involvement in agreement with latest reports

Long Wavelength Anomalous Diffusion Mode in the 2D XY Dipole Magnet

In 2D XY ferromagnet the dipole force induces a strong interaction between spin-waves in the long-wavelength limit. The major effect of this interaction is the transformation of a propagating spin-wave into a diffusion mode. We study the anomalous dynamics of such diffusion modes. We find that the Janssen-De Dominics functional, which governs this dynamics, approaches the non-Gaussian fixed-point. A spin-wave propagates by an anomalous anisotropic diffusion with the dispersion relation: $i\omega{\sim}k_{y}^{\Delta_y}$ and $i\omega{\sim}k_{x}^{\Delta_x}$, where ${\Delta_y}=47/27$ and ${\Delta_x}=47/36$. The low-frequency response to the external magnetic field is found.Comment: 34 pages, RevTeX, 2 .ps figures, the third figure is available upon reques

Dynamics of Particles Deposition on a Disordered Substrate: II. Far-from Equilibrium Behavior. -

The deposition dynamics of particles (or the growth of a rigid crystal) on a disordered substrate at a finite deposition rate is explored. We begin with an equation of motion which includes, in addition to the disorder, the periodic potential due to the discrete size of the particles (or to the lattice structure of the crystal) as well as the term introduced by Kardar, Parisi, and Zhang (KPZ) to account for the lateral growth at a finite growth rate. A generating functional for the correlation and response functions of this process is derived using the approach of Martin, Sigga, and Rose. A consistent renormalized perturbation expansion to first order in the non-Gaussian couplings requires the calculation of diagrams up to three loops. To this order we show, for the first time for this class of models which violates the the fluctuation-dissipation theorem, that the theory is renormalizable. We find that the effects of the periodic potential and the disorder decay on very large scales and asymptotically the KPZ term dominates the behavior. However, strong non-trivial crossover effects are found for large intermediate scales.Comment: 52 pages & 17 Figs in uucompressed file. UR-CM 94-090

An inventory control policy for liquefied natural gas as a transportation fuel

In this paper, we study a novel stochastic inventory management problem that arises in storage and refueling facilities for Liquefied Natural Gas (LNG) as a transportation fuel. In this inventory problem, the physio-chemical properties of LNG play a key role in the design of inventory policies. These properties are: (1) LNG suffers from both quantity decay and quality deterioration and (2) the quality of on-hand LNG can be upgraded by mixing it with higher-quality LNG. Given that LNG quality can be upgraded, an inventory control policy for this problem needs to consider the removal of LNG as a decision variable. We model and solve the problem by means of a Markov Decision Process (MDP) and study the structural characteristics of the optimal policy. The insights obtained in the analysis of the optimal policy are translated into a simple, though effective, inventory control policy in which actions (i.e., replenishment and/or removal) are driven by both the quality and the quantity of the inventories. We assess the performance of our policy by means of a numerical study and show that it performs close to optimal in many numerical instances. The main conclusion of our study is that it is important to take quality into consideration when design inventory control policies for LNG, and that the most effective way to cope with quality issues in an LNG inventory system involves both the removal and the replenishment of inventories